COVID-19 REINFECTIONS & BREAKTHROUGH INFECTIONS

COVID-19 Reinfection Tracker

The COVID-19 Reinfection tracker compiles information and evidence on COVID-19 reinfections from across the world and from India in a publicly accessible resource to aid clinicians, researchers and policy-makers providing them a curated and much needed evidence on re-infections.

Documents

A number of documents released in response to the COVID-19 pandemic have cited the SARS-CoV-2 re-infections reported from our studies.

Reinfection with SARS-CoV-2: considerations for public health response

ECDC Threat Assessment Brief Dated 21 September 2020

Genomics of COVID-19 Reinfections and Vaccine Breakthrough Infections

Re-infection of SARS-CoV-2 is a rare entity. There have been only a few reports of SARS-CoV-2 re-infection reported from across the world. It is widely believed that genetic variants in the SARS-CoV-2 genome are responsible for re-infection. No data is yet available on host factors responsible for re-infection, though some evidence points to the key role of germinal centre development and re-infection, suggesting a potential subtle primary or secondary immunodeficiency.

If you know of a case of reinfection, please let us know. While non-clinicians could suggest a case, we would need a clinician to formally refer the case to us.

In Press & Media

Publications

Gupta V, Bhoyar R, Jain A, Srivastava S, Upadhayay R, Imran M, Jolly B, Divakar M, Sharma D, Sehgal P, Ranjan G, Gupta R, Scaria V, Sivasubbu S

Asymptomatic reinfection in two healthcare workers from India with genetically distinct SARS-CoV-2

Clinical Infectious Diseases (2020)
Yadav SP, Thakkar D, Bhoyar RC, Jain A, Wadhwa T, Imran M, Jolly B, Divakar MK, Kapoor R, Rastogi N, Sharma D, Sehgal P, Ranjan G, Sivasubbu S, Sarma S, Scaria V

Asymptomatic reactivation of SARS-CoV-2 in a Child with Neuroblastoma Characterised by Whole Genome Sequencing

IDCases (2020), e01018,
Rani PR, Imran M, Lakshmi JV, Jolly B, Jain A, Surekha A, Senthivel V, Chandrasekhar P, Divakar MK, Srinivasulu D, Bhoyar RC, Vanaja PR, Scaria V, Sivasubbu S.

Symptomatic reinfection of SARS-CoV-2 with spike protein variant N440K associated with immune escape.

J Med Virol. 2021 Apr 5. doi: 10.1002/jmv.26997. Epub ahead of print. PMID: 33818797.

J, Beena P., Bani Jolly, Neethu John, Rahul C. Bhoyar, Nisha Majeed, Vigneshwar Senthivel, Fairoz C. P, et al. 2021. Genomic Survey of Sars-Cov-2 Vaccine Breakthrough Infections in Healthcare Workers from Kerala, India.OSF Preprints. May 10. doi:10.31219/osf.io/85ndu.